Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
Glioblastoma is thought to arise from neural stem cells. Here, to investigate this, the authors use single-cell RNA-sequencing to compare glioblastoma to the fetal human brain, and find a similarity between glial progenitor cells and a subpopulation of glioblastoma cells.
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17186-5 |