Non-Invasive Delivery of dsRNA into De-Waxed Tick Eggs by Electroporation.

RNA interference-mediated gene silencing was shown to be an efficient tool for validation of targets that may become anti-tick vaccine components. Here, we demonstrate the application of this approach in the validation of components of molecular signaling cascades, such as the Protein Kinase B (AKT)...

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Bibliographic Details
Main Authors: Newton Ruiz, Leonardo Araujo de Abreu, Luís Fernando Parizi, Tae Kwon Kim, Albert Mulenga, Gloria Regina Cardoso Braz, Itabajara da Silva Vaz, Carlos Logullo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4474930?pdf=render