Serum neurofilament light levels in normal aging and their association with morphologic brain changes

Serum neurofilament light levels in normal aging and their association with morphologic brain changes

Neurofilament (NfL) levels in CSF and blood have been established as a biomarker of neuronal damage in neurodegenerative diseases, and there is an age-dependent increase in NfL levels in CSF. Here the authors demonstrate that serum NfL levels increase in healthy aging people and predict and correlat...

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Bibliographic Details
Main Authors: Michael Khalil, Lukas Pirpamer, Edith Hofer, Margarete M. Voortman, Christian Barro, David Leppert, Pascal Benkert, Stefan Ropele, Christian Enzinger, Franz Fazekas, Reinhold Schmidt, Jens Kuhle
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14612-6

Internet

https://doi.org/10.1038/s41467-020-14612-6

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