Attenuated Replication of Lassa Virus Vaccine Candidate ML29 in STAT-1-/- Mice

Lassa virus (LASV), a highly prevalent mammalian arenavirus endemic in West Africa, can cause Lassa fever (LF), which is responsible for thousands of deaths annually. LASV is transmitted to humans from naturally infected rodents. At present, there is not an effective vaccine nor treatment. The genet...

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Bibliographic Details
Main Authors: Dylan M. Johnson, Jenny D. Jokinen, Igor S. Lukashevich
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/8/1/9