Detection and Quantification of Influenza Virus Defective Viral Genomes from NGS Datasets Obtained after RT or RT-PCR Product Sequencing

Detection and Quantification of Influenza Virus Defective Viral Genomes from NGS Datasets Obtained after RT or RT-PCR Product Sequencing

Like most RNA viruses, influenza viruses (IAV) generate defective viral genomes (DVGs) during viral replication. Although there is accumulating evidence of a biological impact of DVGs, the molecular mechanisms leading to their production remain to be unveiled. Various next-generation sequencing (NGS...

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Bibliographic Details
Main Authors: Jeremy Boussier, Sandie Munier, Bernadette Crescenzo-Chaigne, Sylvie Behillil, Vincent Enouf, Sylvie van der Werf, Nadia Naffakh
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
defective viral genomes
influenza
RNA-seq
Online Access:https://www.mdpi.com/2504-3900/50/1/84

Internet

https://www.mdpi.com/2504-3900/50/1/84

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