Fabrication and characterization of solid lipid nano-formulation of astraxanthin against DMBA-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway

Fabrication and characterization of solid lipid nano-formulation of astraxanthin against DMBA-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway

In the current experimental study, we scrutinized the chemoprotective effect of astraxanthin against the 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer via Nrf-2-Keap1 and NF-kB and mTOR/Maf-1/PTEN pathway. The double emulsion solvent displacement method was used for the preparation of...

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Bibliographic Details
Main Authors: Tao Sun, Jun Gao, Dan Han, Hongyan Shi, Xianqiang Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
astraxanthin
solid lipid nanoparticles
breast cancer
antioxidant
hmg-coar
nf-kb
metabolizing enzymes
nrf-2
keap1
Online Access:http://dx.doi.org/10.1080/10717544.2019.1667454

Internet

http://dx.doi.org/10.1080/10717544.2019.1667454

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