Calculation of the Stabilization Energies of Oxidatively Damaged Guanine Base Pairs with Guanine

Calculation of the Stabilization Energies of Oxidatively Damaged Guanine Base Pairs with Guanine

DNA is constantly exposed to endogenous and exogenous oxidative stresses. Damaged DNA can cause mutations, which may increase the risk of developing cancer and other diseases. G:C-C:G transversions are caused by various oxidative stresses. 2,2,4-Triamino-5(2<em>H</em>)-ox...

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Bibliographic Details
Main Authors: Hiroshi Miyazawa, Rie Komori, Takanobu Kobayashi, Katsuhito Kino, Masayuki Morikawa, Masayo Suzuki
Format: Article
Language:English
Published: MDPI AG 2012-06-01
Series:Molecules
Subjects:
oxidative guanine damage
base pair
hydrogen bond
stabilization energy
Online Access:http://www.mdpi.com/1420-3049/17/6/6705

Internet

http://www.mdpi.com/1420-3049/17/6/6705

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