Gut Microbiota Dysbiosis Is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis

Gut Microbiota Dysbiosis Is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis

Liver health, fecal bile acid (BA) concentrations, and gut microbiota composition are closely connected. BAs and the microbiome influence each other in the gut, where bacteria modify the BA profile, while intestinal BAs regulate the growth of commensal bacteria, maintain the barrier integrity, and m...

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Bibliographic Details
Main Authors: Yizhong Wang, Xuefeng Gao, Xinyue Zhang, Yongmei Xiao, Jiandong Huang, Dongbao Yu, Xiaolu Li, Hui Hu, Ting Ge, Dan Li, Ting Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSystems
Subjects:
bile acids
cholestatic jaundice
dysbiosis
gut microbiota
infants
Online Access:https://doi.org/10.1128/mSystems.00463-19

Internet

https://doi.org/10.1128/mSystems.00463-19

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