Kidney Failure Associates With T Cell Exhaustion and Imbalanced Follicular Helper T Cells

Kidney Failure Associates With T Cell Exhaustion and Imbalanced Follicular Helper T Cells

Individuals with kidney failure are at increased risk of cardiovascular events, as well as infections and malignancies, but the associated immunological abnormalities are unclear. We hypothesized that the uremic milieu triggers a chronic inflammatory state that, while accelerating atherosclerosis, p...

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Bibliographic Details
Main Authors: Susan Hartzell, Sofia Bin, Chiara Cantarelli, Meredith Haverly, Joaquin Manrique, Andrea Angeletti, Gaetano La Manna, Barbara Murphy, Weijia Zhang, Josh Levitsky, Lorenzo Gallon, Samuel Mon-Wei Yu, Paolo Cravedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
exhaustion
ESKD
dialysis (ESKD)
T cell
treg
immune phenotype
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.583702/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.583702/full

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