The assembly of individual chaplin peptides from Streptomyces coelicolor into functional amyloid fibrils.

The self-association of proteins into amyloid fibrils offers an alternative to the natively folded state of many polypeptides. Although commonly associated with disease, amyloid fibrils represent the natural functional state of some proteins, such as the chaplins from the soil-dwelling bacterium Str...

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Bibliographic Details
Main Authors: Elizabeth B Sawyer, Dennis Claessen, Maria Haas, Bhavna Hurgobin, Sally L Gras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3079736?pdf=render