T cell receptor repertoire as a prognosis marker for heat shock protein peptide complex-96 vaccine trial against newly diagnosed glioblastoma

T cell receptor repertoire as a prognosis marker for heat shock protein peptide complex-96 vaccine trial against newly diagnosed glioblastoma

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults with a dismal prognosis. We previously reported that vaccination with heat shock protein peptide complex-96 (HSPPC-96) improves survival in patients with newly diagnosed GBM (NCT02122822). Especially for patient...

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Bibliographic Details
Main Authors: Yang Zhang, Poorva Mudgal, Liuyang Wang, Haiyang Wu, Na Huang, Peter B. Alexander, Zhixian Gao, Nan Ji, Qi-Jing Li
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
glioblastoma
tumor vaccine
t cell receptor sequencing
tcr repertoire
gp96
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1749476

Internet

http://dx.doi.org/10.1080/2162402X.2020.1749476

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