The Two-Component System ArlRS and Alterations in Metabolism Enable Staphylococcus aureus to Resist Calprotectin-Induced Manganese Starvation.

During infection the host imposes manganese and zinc starvation on invading pathogens. Despite this, Staphylococcus aureus and other successful pathogens remain capable of causing devastating disease. However, how these invaders adapt to host-imposed metal starvation and overcome nutritional immunit...

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Bibliographic Details
Main Authors: Jana N Radin, Jessica L Kelliher, Paola K Párraga Solórzano, Thomas E Kehl-Fie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5130280?pdf=render