Mutation of Gemin5 Causes Defective Hematopoietic Stem/Progenitor Cells Proliferation in Zebrafish Embryonic Hematopoiesis

Mutation of Gemin5 Causes Defective Hematopoietic Stem/Progenitor Cells Proliferation in Zebrafish Embryonic Hematopoiesis

Fate determination and expansion of Hematopoietic Stem and Progenitor Cells (HSPCs) is tightly regulated on both transcriptional and post-transcriptional level. Although transcriptional regulation of HSPCs have achieved a lot of advances, its post-transcriptional regulation remains largely underexpl...

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Bibliographic Details
Main Authors: Xiaofen Liu, Wenjuan Zhang, Changbin Jing, Lei Gao, Cong Fu, Chunguang Ren, Yimei Hao, Mengye Cao, Ke Ma, Weijun Pan, Dantong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Gemin5
Hematopoietic stem/progenitor cells
cell proliferation
zebrafish
definitive hematopoiesis
forward genetic screening
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.670654/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.670654/full

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