α-Lipoic Acid Targeting PDK1/NRF2 Axis Contributes to the Apoptosis Effect of Lung Cancer Cells

As an antioxidant, α-lipoic acid (LA) has attracted much attention to cancer research. However, the exact mechanism of LA in cancer progression control and prevention remains to be unclear. In this study, we demonstrated that α-lipoic acid has inhibitory effects on the proliferation, migration, and...

Full description

Bibliographic Details
Main Authors: Liduo Yue, Yanbei Ren, Qingxi Yue, Zhou Ding, Kai Wang, Tiansheng Zheng, Guojie Chen, Xiangyun Chen, Ming Li, Lihong Fan
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6633419