Allium macrostemon Saponin Inhibits Activation of Platelet via the CD40 Signaling Pathway

Allium macrostemon Saponin Inhibits Activation of Platelet via the CD40 Signaling Pathway

Allium macrostemon saponin is a traditional Chinese medicine that exhibits anti-atherosclerosis effects. However, the mechanism of its action has not been fully clarified. Platelet activation induced by CD40L plays an important role in the process of atherosis. In the present study, we demonstrate f...

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Bibliographic Details
Main Authors: Sisi Ling, Lijun Jin, Shizheng Li, Fangcheng Zhang, Qiong Xu, Mingke Liu, Xuke Chen, Xiaolin Liu, Jielei Gu, Shiming Liu, Ningning Liu, Wenchao Ou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Allium macrostemon saponin
platelet activation
CD40
TRAF2
degradation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.570603/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.570603/full

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