Using ordinal outcomes to construct and select biomarker combinations for single-level prediction

Abstract Background Biomarker studies may involve an ordinal outcome, such as no, mild, or severe disease. There is often interest in predicting one particular level of the outcome due to its clinical significance. Methods A simple approach to constructing biomarker combinations in this context invo...

Full description

Bibliographic Details
Main Authors: Allison Meisner, Chirag R. Parikh, Kathleen F. Kerr
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Diagnostic and Prognostic Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41512-018-0028-3