Early administration of dapagliflozin preserves pancreatic β‐cell mass through a legacy effect in a mouse model of type 2 diabetes

Early administration of dapagliflozin preserves pancreatic β‐cell mass through a legacy effect in a mouse model of type 2 diabetes

Abstract Aims/Introduction The preservation of pancreatic β‐cell mass is an essential factor in the onset and development of type 2 diabetes mellitus. Recently, sodium–glucose cotransporter 2 inhibitors have been launched as antihyperglycemic agents, and their organ‐protective effects are attracting...

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Bibliographic Details
Main Authors: Ayumi Kanno, Shun‐ichiro Asahara, Mao Kawamura, Ayuko Furubayashi, Shoko Tsuchiya, Emi Suzuki, Tomoko Takai, Maki Koyanagi‐Kimura, Tomokazu Matsuda, Yuko Okada, Wataru Ogawa, Yoshiaki Kido
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Journal of Diabetes Investigation
Subjects:
Pancreatic β‐cell
Sodium–glucose cotransporter 2
Type 2 diabetes mellitus
Online Access:https://doi.org/10.1111/jdi.12945

Internet

https://doi.org/10.1111/jdi.12945

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