Chronic antidepressant treatment accelerates kindling epileptogenesis in rats

Chronic antidepressant treatment accelerates kindling epileptogenesis in rats

Objectives: Due to the high comorbidity of epilepsy and depression, antidepressant treatment is commonly indicated for patients with epilepsy. Studies in humans and animal models suggest that selective serotonin reuptake inhibitors (SSRIs) may reduce seizure frequency and severity, and these drugs a...

Full description

Bibliographic Details
Main Authors: Lisa Cardamone, Michael R. Salzberg, Amelia S. Koe, Ezgi Ozturk, Terence J. O'Brien, Nigel C. Jones
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Neurobiology of Disease
Subjects:
Selective serotonin reuptake inhibitor
Epilepsy
Antidepressant
Depression
Epileptogenesis
Animal model
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113003331

Internet

http://www.sciencedirect.com/science/article/pii/S0969996113003331

Similar Items