Chronic antidepressant treatment accelerates kindling epileptogenesis in rats
Objectives: Due to the high comorbidity of epilepsy and depression, antidepressant treatment is commonly indicated for patients with epilepsy. Studies in humans and animal models suggest that selective serotonin reuptake inhibitors (SSRIs) may reduce seizure frequency and severity, and these drugs a...
Main Authors: | Lisa Cardamone, Michael R. Salzberg, Amelia S. Koe, Ezgi Ozturk, Terence J. O'Brien, Nigel C. Jones |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-03-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996113003331 |
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