Effect of 3'UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma.

Effect of 3'UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma.

BACKGROUND:The RET S836S variant has been associated with early onset and increased risk for metastatic disease in medullary thyroid carcinoma (MTC). However, the mechanism by which this variant modulates MTC pathogenesis is still open to discuss. Of interest, strong linkage disequilibrium (LD) betw...

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Main Authors: Lucieli Ceolin, Mirian Romitti, Débora Rodrigues Siqueira, Carla Vaz Ferreira, Jessica Oliboni Scapineli, Beatriz Assis-Brazil, Rodolfo Vieira Maximiano, Tauanne Dias Amarante, Miriam Celi de Souza Nunes, Gerald Weber, Ana Luiza Maia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4734678?pdf=render

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http://europepmc.org/articles/PMC4734678?pdf=render

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