The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure.

The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure.

Plasmodium falciparum malaria parasites, living in red blood cells, express proteins of the erythrocyte membrane protein-1 (PfEMP1) family on the red blood cell surface. The binding of PfEMP1 molecules to human cell surface receptors mediates the adherence of infected red blood cells to human tissue...

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Bibliographic Details
Main Authors: Michael M Klein, Apostolos G Gittis, Hua-Poo Su, Morris O Makobongo, Jaime M Moore, Sanjay Singh, Louis H Miller, David N Garboczi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2518858?pdf=render

Internet

http://europepmc.org/articles/PMC2518858?pdf=render

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