Regulation of Acetylcholine Quantal Release by Coupled Thrombin/BDNF Signaling in Mouse Motor Synapses

Regulation of Acetylcholine Quantal Release by Coupled Thrombin/BDNF Signaling in Mouse Motor Synapses

The aim of this study was to compare the acute effects of thrombin and brain-derived neurotrophic factor (BDNF) on spontaneous miniature endplate potentials (MEPPs) and multiquantal evoked endplate potentials (EPPs) in mouse neuromuscular junctions (NMJs) of m. diaphragma and m. EDL. Intracellular m...

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Bibliographic Details
Main Authors: Alexander Gaydukov, Polina Bogacheva, Ekaterina Tarasova, Anastasia Molchanova, Anna Miteva, Ekaterina Pravdivceva, Olga Balezina
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
endplate potentials
neuromuscular junction
thrombin
BDNF
TrkB
MEK1/2
A<sub>2A</sub> receptors
PKA
PLC
Online Access:https://www.mdpi.com/2073-4409/8/7/762

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https://www.mdpi.com/2073-4409/8/7/762

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