Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses

Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses

Seasonal exposure to birch pollen (BP) is a major cause of pollinosis. The specific role of Toll-like receptor 4 (TLR4) in BP-induced allergic inflammation and the identification of key factors in birch pollen extracts (BPE) initiating this process remain to be explored. This study aimed to examine...

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Bibliographic Details
Main Authors: Lisa Pointner, Amin Kraiem, Michael Thaler, Fabian Richter, Mario Wenger, Athanasios Bethanis, Markus Klotz, Claudia Traidl-Hoffmann, Stefanie Gilles, Lorenz Aglas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Allergy
Subjects:
allergic sensitization
T cell response
dendritic cells
innate immunity
TLR4 signaling
birch pollen
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2021.680937/full

Internet

https://www.frontiersin.org/articles/10.3389/falgy.2021.680937/full

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