Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models
Chikungunya virus (CHIKV) is a reemerging arbovirus capable of causing explosive outbreaks of febrile illness, polyarthritis, and polyarthralgia, inflicting severe morbidity on affected populations. CHIKV can be genetically classified into 3 major lineages: West African (WA); East, Central, and Sout...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-03-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/9/2/e02449-17 |