Transfer posterior error probability estimation for peptide identification

Transfer posterior error probability estimation for peptide identification

Abstract Background In shotgun proteomics, database searching of tandem mass spectra results in a great number of peptide-spectrum matches (PSMs), many of which are false positives. Quality control of PSMs is a multiple hypothesis testing problem, and the false discovery rate (FDR) or the posterior...

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Bibliographic Details
Main Authors: Xinpei Yi, Fuzhou Gong, Yan Fu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
Proteomics
Mass spectrometry
Quality control
Posterior error probability
Local false discovery rate
Transfer learning
Online Access:http://link.springer.com/article/10.1186/s12859-020-3485-y

Internet

http://link.springer.com/article/10.1186/s12859-020-3485-y

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