Synthesis of Natural O-Linked Carba-Disaccharides, (+)- and (−)-Pericosine E, and Their Analogues as α-Glucosidase Inhibitors

Synthesis of Natural O-Linked Carba-Disaccharides, (+)- and (−)-Pericosine E, and Their Analogues as α-Glucosidase Inhibitors

Pericosine E (6), a metabolite of Periconia byssoides OUPS-N133 was originally isolated from the sea hare Aplysia kurodai, which exists as an enantiomeric mixture in nature. The enantiospecific syntheses of both enantiomers of Periconia byssoides OUPS-N133 has been achieved, along with six stereoiso...

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Bibliographic Details
Main Authors: Yoshihide Usami, Koji Mizuki, Rikiya Kawahata, Makio Shibano, Atsuko Sekine, Hiroki Yoneyama, Shinya Harusawa
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Marine Drugs
Subjects:
synthesis
pericosine E
marine natural product
O-linked carba-disaccharide
α-glucosidase inhibitor
enantiomeric mixture
Online Access:http://www.mdpi.com/1660-3397/15/1/22

Internet

http://www.mdpi.com/1660-3397/15/1/22

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