Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells

Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells

Application of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) is limited by the challenges in their efficient differentiation. Recently, the Wingless (Wnt) signaling pathway has emerged as the key regulator of cardiomyogenesis. In this study, we evaluated the effects of cyclooxygenase...

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Bibliographic Details
Main Authors: Harshal Nemade, Aviseka Acharya, Umesh Chaudhari, Erastus Nembo, Filomain Nguemo, Nicole Riet, Hinrich Abken, Jürgen Hescheler, Symeon Papadopoulos, Agapios Sachinidis
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
pluripotent stem cells
cardiomyocytes
differentiation
sulindac
small molecules
wnt pathway
cyclooxygenase pathway
Online Access:https://www.mdpi.com/2073-4409/9/3/554

Internet

https://www.mdpi.com/2073-4409/9/3/554

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