Sec translocon has an insertase-like function in addition to polypeptide conduction through the channel [version 1; peer review: 4 approved]
The Sec translocon provides a polypeptide-conducting channel, which is insulated from the hydrophobic lipidic environment of the membrane, for translocation of hydrophilic passenger polypeptides. Its lateral gate allows a downstream hydrophobic segment (stop-transfer sequence) to exit the channel la...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2019-12-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-2126/v1 |