BDNF Gene's Role in Schizophrenia: From Risk Allele to Methylation Implications

Background: Schizophrenia (SZ) is a severe chronic mental disorder with complex genetic mechanisms. Brain-derived neurotrophic factor (BDNF) is one of promising candidate genes for SZ, and rs6265 is a non-synonymous single nucleotide polymorphism (SNP) in BDNF.Methods: In this study, we performed a...

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Bibliographic Details
Main Authors: Xiaoqian Fu, Jun Wang, Jianbin Du, Jing Sun, Ancha Baranova, Fuquan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2020.564277/full