Modulation of PTZ induced seizures by Citrus aurantium in zebrafish: role of NMDA and metabotropic glutamate receptors.

Modulation of PTZ induced seizures by Citrus aurantium in zebrafish: role of NMDA and metabotropic glutamate receptors.

Citrus aurantium (CA), commonly known as bitter orange, is used in folk medicine to treat anxiety and insomnia. Studies performed with Essential oils from the peel of the fruit have shown to increase seizure latency to pentylenetetrazole (PTZ) and maximal electroshock seizure in animal models. With...

Full description

Bibliographic Details
Main Authors: Coral eRosa-Falero, Stephanie eTorres-Rodríguez, Claudia eClaudia Jordán, Rígel eLicier, Yolimar eSantiago, Zuleyma eToledo, Marely eSantiago, Kiara eSerrano, José G. Ortiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Pharmacology
Subjects:
Epilepsy
Zebrafish
Glutamate
Natural Products
Citrus aurantium
Puertorrican folklore
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00284/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00284/full

Similar Items