Non-Enzymatic Modification of Aminophospholipids by Carbonyl-Amine Reactions

Non-Enzymatic Modification of Aminophospholipids by Carbonyl-Amine Reactions

Non-enzymatic modification of aminophospholipids by lipid peroxidation-derived aldehydes and reducing sugars through carbonyl-amine reactions are thought to contribute to the age-related deterioration of cellular membranes and to the pathogenesis of diabetic complications. Much evidence demonstrates...

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Bibliographic Details
Main Authors: Reinald Pamplona, Manuel Portero-Otín, Rosanna Cabré, Victòria Ayala, Mariona Jové, Alba Naudí
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
advanced glycation endproducts
advanced lipoxidation endproducts
age-associated diseases
aging
cell membrane
carbonyl compounds
lipid peroxidation
Maillard reaction products
oxidative stress
phosphatidylethanolamine
phosphatidylserine
Online Access:http://www.mdpi.com/1422-0067/14/2/3285

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http://www.mdpi.com/1422-0067/14/2/3285

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