An Efficient Cell-Targeting Drug Delivery System Based on Aptamer-Modified Mesoporous Silica Nanoparticles

Abstract How to deliver chemotherapeutic drugs efficiently and selectively to tumor cells to improve therapeutic efficacy remains a difficult problem. We herein construct an efficient cell-targeting drug delivery system (Sgc8-MSN/Dox) based on aptamer-modified mesoporous silica nanoparticles that re...

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Bibliographic Details
Main Authors: Yang Yang, Weihua Zhao, Wenwen Tan, Zongqiang Lai, Dong Fang, Lei Jiang, Chuantian Zuo, Nuo Yang, Yongrong Lai
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:Nanoscale Research Letters
Subjects:
Online Access:https://doi.org/10.1186/s11671-019-3208-3