Human COQ10A and COQ10B are distinct lipid-binding START domain proteins required for coenzyme Q function[S]

Human COQ10A and COQ10B are distinct lipid-binding START domain proteins required for coenzyme Q function[S]

Coenzyme Q (CoQ or ubiquinone) serves as an essential redox-active lipid in respiratory electron and proton transport during cellular energy metabolism. CoQ also functions as a membrane-localized antioxidant protecting cells against lipid peroxidation. CoQ deficiency is associated with multiple huma...

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Bibliographic Details
Main Authors: Hui S. Tsui, NguyenV.B. Pham, Brendan R. Amer, Michelle C. Bradley, Jason E. Gosschalk, Marcus Gallagher-Jones, Hope Ibarra, Robert T. Clubb, Crysten E. Blaby-Haas, Catherine F. Clarke
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Lipid Research
Subjects:
antioxidants
lipids/chemistry
lipids/peroxidation
mass spectrometry
mitochondria
Saccharomyces cerevisiae
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520310610

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http://www.sciencedirect.com/science/article/pii/S0022227520310610

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