Ten-Hour Exposure to Low-Dose Ketamine Enhances Corticostriatal Cross-Frequency Coupling and Hippocampal Broad-Band Gamma Oscillations

Introduction: Treatment-resistant depression, post-traumatic stress disorder, chronic pain, and L-DOPA-induced dyskinesia in Parkinson’s disease are characterized by hypersynchronous neural oscillations. Sub-anesthetic ketamine is effective at treating these conditions, and this may relate to ketami...

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Bibliographic Details
Main Authors: Tony Ye, Mitchell J. Bartlett, Matthew B. Schmit, Scott J. Sherman, Torsten Falk, Stephen L. Cowen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2018.00061/full