Neurovascular effects of umbilical cord blood-derived stem cells in growth-restricted newborn lambs

Neurovascular effects of umbilical cord blood-derived stem cells in growth-restricted newborn lambs

Abstract Background Neonatal ventilation exacerbates brain injury in lambs with fetal growth restriction (FGR), characterized by neuroinflammation and reduced blood-brain barrier integrity, which is normally maintained by the neurovascular unit. We examined whether umbilical cord blood stem cell (UC...

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Bibliographic Details
Main Authors: Atul Malhotra, Margie Castillo-Melendez, Beth J. Allison, Amy E. Sutherland, Ilias Nitsos, Yen Pham, Courtney A. McDonald, Michael C. Fahey, Graeme R. Polglase, Graham Jenkin, Suzanne L. Miller
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Brain injury
Intrauterine growth restriction
IUGR
FGR
Preterm
Ventilation
Online Access:https://doi.org/10.1186/s13287-019-1526-0

Internet

https://doi.org/10.1186/s13287-019-1526-0

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