IL-17A induces endothelial inflammation in systemic sclerosis via the ERK signaling pathway.

Recent reports have demonstrated that endothelial cells are involved in vascular inflammatory injury in systemic sclerosis (SSc) and interleukin-17A (IL-17A) plays a crucial role in the pathogenesis of SSC. However, little is known about the effects of IL-17A on endothelial cell inflammation in SSC....

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Bibliographic Details
Main Authors: Xiaojing Xing, Ji Yang, Xiaoqin Yang, Yi Wei, Lubing Zhu, Di Gao, Ming Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3871633?pdf=render