Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury

Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury

Background: Renal ischemia-reperfusion injury (IRI) is a major factor contributing to acute kidney injury and it is associated with a high morbidity and mortality if untreated. Renal IRI depletes cellular and tissue adenosine triphosphate (ATP), which compromises mitochondrial function, further exac...

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Bibliographic Details
Main Authors: Meiwen Ding, Evelyn Tolbert, Mark Birkenbach, Reginald Gohh, Fatemeh Akhlaghi, Nisanne S. Ghonem
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Acute kidney injury
Prostacyclin
Mitochondria
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221006946

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http://www.sciencedirect.com/science/article/pii/S0753332221006946

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