An ex vivo model for anti-angiogenic drug testing on intact microvascular networks.

New models of angiogenesis that mimic the complexity of real microvascular networks are needed. Recently, our laboratory demonstrated that cultured rat mesentery tissues contain viable microvascular networks and could be used to probe pericyte-endothelial cell interactions. The objective of this stu...

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Bibliographic Details
Main Authors: Mohammad S Azimi, Leann Myers, Michelle Lacey, Scott A Stewart, Qirong Shi, Prasad V Katakam, Debasis Mondal, Walter L Murfee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4350846?pdf=render