Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.

<h4>Background</h4>Radiotherapy kills tumor-cells by inducing DNA double strand breaks (DSBs). However, the efficient repair of tumors frequently prevents successful treatment. Therefore, identifying new practical sensitizers is an essential step towards successful radiotherapy. In this...

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Bibliographic Details
Main Authors: Dan Yan, Wooi Loon Ng, Xiangming Zhang, Ping Wang, Zhaobin Zhang, Yin-Yuan Mo, Hui Mao, Chunhai Hao, Jeffrey J Olson, Walter J Curran, Ya Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20617180/pdf/?tool=EBI