Molecular and Chemical Regulation of the Keap1-Nrf2 Signaling Pathway

Extracellular and intracellular oxidants or electrophiles are key contributors to the damages in cellular macromolecules, such as DNA, proteins and lipids. Nrf2 is a master transcription factor that modulates a cellular antioxidant response program and plays an important role in the protection agai...

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Bibliographic Details
Main Authors: Young-Sam Keum, Bu Young Choi
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
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Online Access:http://www.mdpi.com/1420-3049/19/7/10074