Analyzing cancer gene expression data through the lens of normal tissue-specificity.
The genetic alterations that underlie cancer development are highly tissue-specific with the majority of driving alterations occurring in only a few cancer types and with alterations common to multiple cancer types often showing a tissue-specific functional impact. This tissue-specificity means that...
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-06-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1009085 |