Weighted Gene Coexpression Network Analysis Reveals Essential Genes and Pathways in Bipolar Disorder

Weighted Gene Coexpression Network Analysis Reveals Essential Genes and Pathways in Bipolar Disorder

Bipolar disorder (BD) is a major and highly heritable mental illness with severe psychosocial impairment, but its etiology and pathogenesis remains unclear. This study aimed to identify the essential pathways and genes involved in BD using weighted gene coexpression network analysis (WGCNA), a bioin...

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Bibliographic Details
Main Authors: Zhen-Qing Zhang, Wei-Wei Wu, Jin-Dong Chen, Guang-Yin Zhang, Jing-Yu Lin, Yan-Kun Wu, Yu Zhang, Yun-Ai Su, Ji-Tao Li, Tian-Mei Si
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Psychiatry
Subjects:
bipolar disorders
coexpression modules
hub genes
WGCNA
pathway analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.553305/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.553305/full

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