Protease-activated receptors and inflammatory hyperalgesia
Recent advances in basic science pointed to a role for proteinases, through the activation of proteinase-activated receptors (PARs) in nociceptive mechanisms. Activation of PAR1, PAR2 and PAR4 either by proteinases or by selective agonists causes inflammation inducing most of the cardinal signs of i...
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| Format: | Article |
| Language: | English |
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Instituto Oswaldo Cruz, Ministério da Saúde
2005-03-01
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| Series: | Memórias do Instituto Oswaldo Cruz. |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900029 |