Antidromic Spike Propagation and Dissimilar Expression of P2X, 5-HT, and TRPV1 Channels in Peripheral vs. Central Sensory Axons in Meninges

Background: The terminal branches of the trigeminal nerve in meninges are supposed to be the origin site of migraine pain. The main function of these peripheral sensory axons is the initiation and propagation of spikes in the orthodromic direction to the second order neurons in the brainstem. The st...

Full description

Bibliographic Details
Main Authors: Oleg Gafurov, Kseniia Koroleva, Rashid Giniatullin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ATP
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.623134/full