Elimination of tumor hypoxia by eribulin demonstrated by 18F-FMISO hypoxia imaging in human tumor xenograft models

Elimination of tumor hypoxia by eribulin demonstrated by 18F-FMISO hypoxia imaging in human tumor xenograft models

Abstract Background Eribulin, an inhibitor of microtubule dynamics, shows antitumor potency against a variety of solid cancers through its antivascular activity and remodeling of tumor vasculature. 18F-Fluoromisonidazole (18F-FMISO) is the most widely used PET probe for imaging tumor hypoxia. In thi...

Full description

Bibliographic Details
Main Authors: Songji Zhao, Wenwen Yu, Naoyuki Ukon, Chengbo Tan, Ken-ichi Nishijima, Yoichi Shimizu, Kei Higashikawa, Tohru Shiga, Hiroko Yamashita, Nagara Tamaki, Yuji Kuge
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:EJNMMI Research
Subjects:
Eribulin
Tumor hypoxia
18F-FMISO PET imaging
Remodeling of tumor vasculature
Human tumor xenograft model
Online Access:http://link.springer.com/article/10.1186/s13550-019-0521-x

Internet

http://link.springer.com/article/10.1186/s13550-019-0521-x

Similar Items