Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis

Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis

Abstract Background Pneumococcal meningitis remains a potentially lethal and debilitating disease, mainly due to brain damage from sustained inflammation. The release of danger-associated molecular patterns (DAMPs), like myeloid-related protein 14 (MRP14) and high mobility group box 1 protein (HMGB1...

Full description

Bibliographic Details
Main Authors: Ilias Masouris, Matthias Klein, Susanne Dyckhoff, Barbara Angele, H. W. Pfister, Uwe Koedel
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Neuroinflammation
Subjects:
Streptococcus pneumoniae
Meningitis
HMGB1
Paquinimod
Adjuvant treatment
Online Access:http://link.springer.com/article/10.1186/s12974-017-0989-0

Internet

http://link.springer.com/article/10.1186/s12974-017-0989-0

Similar Items