3-Bromo-4,5-dihydroxybenzaldehyde Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes

3-Bromo-4,5-dihydroxybenzaldehyde Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes

A natural bromophenol found in seaweeds, 3-bromo-4,5-dihydroxybenzaldehyde (BDB), has been shown to possess antioxidant effects. This study aimed to investigate the mechanism by which BDB protects skin cells subjected to oxidative stress. The effect of BDB on the protein and mRNA levels of glutathio...

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Bibliographic Details
Main Authors: Ki Cheon Kim, Yu Jae Hyun, Susara Ruwan Kumara Madduma Hewage, Mei Jing Piao, Kyoung Ah Kang, Hee Kyoung Kang, Young Sang Koh, Mee Jung Ahn, Jin Won Hyun
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Marine Drugs
Subjects:
3-bromo-4,5-dihydroxybenzaldehyde
glutathione
oxidative stress
glutathione synthetase
NF-E2 related factor 2
Online Access:https://www.mdpi.com/1660-3397/15/9/291

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https://www.mdpi.com/1660-3397/15/9/291

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