Preparation of Poly (dl-Lactide-co-Glycolide) Nanoparticles Encapsulated with Periglaucine A and Betulinic Acid for In Vitro Anti-Acanthamoeba and Cytotoxicity Activities

Poly (dl-lactide-co-glycolide) (PLGA) microspheres were synthesized as delivery system for the natural anti-parasitic compounds, Periglaucine A (PGA) and Betulinic acid (BA). Periglaucine A and Betulinic acid were encapsulated in PLGA nanoparticles by single emulsion method with an average particle...

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Bibliographic Details
Main Authors: Tooba Mahboob, Muhammad Nawaz, Tan Tian-Chye, Chandramathi Samudi, Christophe Wiart, Veeranoot Nissapatorn
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/7/3/62