The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis

The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis

The VLDL receptor (VLDLr) is involved in tissue delivery of VLDL-triglyceride (TG)-derived FFA by facilitating the expression of lipoprotein lipase (LPL). However, vldlr−/− mice do not show altered plasma lipoprotein levels, despite reduced LPL expression. Because LPL activity is crucial in postpran...

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Bibliographic Details
Main Authors: Jeltje R. Goudriaan, Sonia M. S. Espirito Santo, Peter J. Voshol, Bas Teusink, Ko Willems van Dijk, Bart J.M. van Vlijmen, Johannes A. Romijn, Louis M. Havekes, Patrick C.N. Rensen
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Journal of Lipid Research
Subjects:
adipose tissue
free fatty acids
lipoprotein lipase
postprandial lipid metabolism
very low density lipoprotein-like emulsion
transgenic mice
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313092

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http://www.sciencedirect.com/science/article/pii/S0022227520313092

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