Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer.

Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer.

INTRODUCTION: Numerous factors influence the development of gastrointestinal (GI) cancer. The insulin-like growth factor (IGF) axis plays a role in embryonic and postnatal growth and tissue repair. Elevated levels of IGFs, low levels of IGF binding proteins (IGFBPs) and over-expression of IGF recept...

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Bibliographic Details
Main Authors: Jennie Ong, Jody Salomon, Rene H M te Morsche, Hennie M J Roelofs, Ben J M Witteman, Polat Dura, Martin Lacko, Wilbert H M Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946608?pdf=render

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http://europepmc.org/articles/PMC3946608?pdf=render

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